Arginine Derivatives as Polyglutamine Aggregation Inhibitors
Non-Confidential description of the invention
The present invention discloses a pharmaceutical composition comprising, arginine derivatives responsible for inhibiting peptide aggregation and maintaining their solubility and stability inside the cell. The arginine derivatives have been evaluated for inhibition of aggregation of gene encoded polyglutamine rich peptide fragments which are responsible for various neurodegenerative diseases like Huntington’s disease.
Dr.Ashwani Kumar Thakur(BSBE) & Mr.Virendra Singh(PhD Student,BSBE)
Date of Filing