Fullerene Nanoparticles and Compositions Thereof for Inhibiting Autophagy

Non-Confidential description of the invention

The invention relate to nanoparticles and their application in regenerative medicine as nano-medicine, and more particularly to fullerene nanoparticles and compositions thereof, for inhibiting autophagy and inducing cell proliferation. The fullerene soot is a fine powder which is composed of a mix of C60 and C70 fullerenes roughly in a ratio of 22% C60 to 76% C70. Fullerene nanoparticles having aggluromate of size 240 to 550 nm for treatment of autophagy associated disorders are suggested. Fullerene nanoparticles are dissolved in the medium and treatment of the same is given to the cells. Fullerene nanoparticles are dissolved in saline and intranasal treatment is given to the mice.


Dr. Ashwani K Thakur (BSBE), Dr. Rituraj Niranjan (BSBE), Mr. Kaushal Prasad Mishra (Project Associate,BSBE)



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