Micro-RNA and Methods to Improve AAV Gene Expression and Vector Production
Non-Confidential description of the invention
The present invention relates to a method for improving AAV mediated gene expression and AAV packaging efficiency. The method comprises the steps of transfecting a host cell by an AAV vector using the triple transfection protocol and co-transfecting the host cell using plasmids encoding miRs. Also relates to micro-RNA based strategies to improve gene expression from AAV vectors and to improve AAV packaging efficiency. It is a method of improving gene expression from AAV vectors and improving AAV packaging efficiency.
Date of Filing