Micro-RNA and Methods to Improve AAV Gene Expression and Vector Production

Non-Confidential description of the invention

The present invention relates to a method for improving AAV mediated gene expression and AAV packaging efficiency. The method comprises the steps of transfecting a host cell by an AAV vector using the triple transfection protocol and co-transfecting the host cell using plasmids encoding miRs. Also relates to micro-RNA based strategies to improve gene expression from AAV vectors and to improve AAV packaging efficiency. It is a method of improving gene expression from AAV vectors and improving AAV packaging efficiency.

Inventors

Dr.J.G.Rao (BSBE)

IPA

201611036719

Date of Filing

26/10/2016

Status

Date Of Grant

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